Hi Aspirant,

Hope you are doing great as per the question asked by you if you have a permanent address of Uttar pradesh then you can certainly apply for domicile quota in Uttar pradesh which will certainly give 85% home state quota. If you are availing state quota of Uttar pradesh then you can not avail domicile quota for any other states.

Hope you found this answer useful.Stay motivated stay positive.

All the best!