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What is Grignard reagent? How is it prepared? why are they prepared under anhydrous condition?


Siddharth Wankhade 11th Jul, 2021
Answers (2)
susanna.maryb 11th Jul, 2021

Hello Aspirant,

Grignard reagents are alkyl, vinyl and Aryl magnesium halides R-MgX. They form very strong carbon - carbon bonds and they are used syntheticaly for this purpose. Grignard Reagents are prepared by treating an organic halide (usually organobromine) with magnesium metal. Ethers (cyclic or acyclic) are required to stabilize the organomagnesium compound. Water and air are agents that rapidly destroy the reagent by protonolysis or oxidation are excluded using air free methods. This is also why Grignard reagents are prepared under anhydrous conditions, because it is very reactive. It reacts with any source of proton to give a hydrocarbon. It reacts with water really quickly. Therefore it is necessary to avoid moisture content.

Hope this helps and Good luck

Aditya 11th Jul, 2021

Hi aspirant,

Grignard reagent chemical compound with the generic formula R−Mg−X, where X is a halogen and R is an alkyl or aryl group. Grignard reagent are commonly used for various organic synthesis reactions.

These reagents are prepared via the treatment of magnesium with alkyl/aryl halides. These are prepared under anhydrous condition because they react abruptly with moisture present in air to form non desirable substances.

Hope it helps!!

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