AP Medical Seats are categorised into AU, SVU, OU areas. The cut offs for ST Category of these areas are as follows:

AU: 378

SVU: 418

OU: 421

So based on the area you belong to, your marks should be atleast 50-75 marks greater than the previous year cut offs. Having said that, cut offs change every year and are dependant on various factors like no.of seats available, no.of candidates appearing for the exam, top NEET score and difficulty of the exam. You can also check the cut offs of various different colleges under your Category at:

https://medicine.careers360.com/articles/neet-cutoff-ap/amp